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At SirenOpt, we transform measurement blind spots into rich multi-layered material insights

Jared O'Leary
CEO & Co-founder
Our Mission

We revolutionize advanced materials characterization with cold atmospheric plasma, machine learning, and predictive analytics to unlock real-time, multi-layered insights, enhancing R&D, performance, and production quality.

Our Investors
About us

Our Origin

SirenOpt is a spin-out from the Mesbah Lab at UC Berkeley's Chemical & Biomolecular Engineering Department. Co-founded by Jared O'Leary, Ali Mesbah, and Joel Paulson, the company specializes in using cold atmospheric plasmas (CAPs) for real-time, non-destructive advanced materials metrology. Initially focused on CAPs for treatment, the team discovered that CAPs could reveal detailed material fingerprints through visual, electrical, thermal, and spectroscopic data. After early success with battery startups, SirenOpt joined the Berkeley SkyDeck Accelerator and the Activate Fellowship, securing $6.6 million in Seed Funding in July 2024. The company's expertise lies in low-energy plasma control, machine learning, and optimized decision-making for advanced process and equipment control.
Founding
SirenOpt is a commercial spin-out from the Mesbah Lab in the Chemical & Biomolecular Engineering Department at the University of California, Berkeley.  At the Mesbah Lab SirenOpt’s co-founders (Jared O’Leary, Ali Mesbah, and Joel Paulson) were broadly interested in investigating learning-based methods for characterizing, modeling, and controlling intrinsically stochastic systems with nonlinear dynamics , including systems of cold atmospheric plasmas (CAPs), or atmospheric pressure plasmas , weakly ionized gases that sit near room temperature.
Cold Atmospheric Plasma
Though CAPs have been deployed in industry for decades to treat and clean complex materials, SirenOpt’s co-founders realized that they could maintain CAPs at extremely low energy levels that could allow the CAPs to non-destructively interact with these complex materials.  They further realized that the resulting CAP-material interactions could reveal vast amounts of visual, electrical, thermal and spectroscopic data about materials and create uniquely distinctive, multifaceted material fingerprints in real-time.
The Idea Behind
Thus, the idea of SirenOpt was born, as SirenOpt’s co-founders “accidentally” discovered the CAP system they were investigating for treatment applications could be used as a real-time, non-destructive, advanced materials metrology platform.  Early traction with Bay Area battery start-up companies then led SirenOpt to be accepted into the Berkeley SkyDeck Accelerator and the Activate Fellowship.
Support and funding
Support from these two programs allowed SirenOpt to progress quickly, culminating in a $6.6m Seed Funding Round that closed in July 2024. SirenOpt’s core technology expertise and intellectual property includes low-energy plasma control, machine learning and optimized decision making for advanced process and equipment control.
Our Vision

Accelerating sustainable, smart manufacturing of advanced materials through intelligent characterization and real-time decision-making.

Meet our team

Our philosophy is simple — hire a team of diverse, passionate people and foster a culture that empowers you to do your best work.

Co-Founders

Jared O’Leary
Founder & CEO
SirenOpt
Ali Mesbah
Associate Professor
UC Berkeley
Joel Paulson
Assistant Professor
The Ohio State University

Leadership

Jared O’Leary
Founder & CEO
John Busch
Chief Operating Officer
James Carrington
VP Sales and Marketing
Yakov Bobrov
VP Engineering

Board of Directors

Jared O’Leary
Founder & CEO
Matthew Blain
Voyager Ventures
Phil Harper
Independent Director
Thong Le Hoang
Visionaries Tomorrow

SirenOpt Advisors

Michelle Meng-Hsiung Kiang
Investor and executive
Jonathan Tan
CEO and co-founder at Coreshell
Steven Kaye
Former CTO of Our Next Energy
John Matranga
Former executive at AVEVA/OSIsoft
Tom Gwinn
Corporate Investor at Evonik
Roland Trassl
Former product manager and research manager at Applied Materials
Our Supporters

Let's talk about your needs

We help companies and start-ups around the world to accelerate sustainable and smart manufacturing of advanced materials.